The 7 best supplements for GERD sufferers

2) Endefen: I consider Endefen to be one of the most valuable weapons in my arsenal against GERD. Usually, I’m wary of multi-ingredient supplements for GI problems because of the potential for intolerance of one or another of the constituents, but the formulators of Endefen seem to have gotten it just right. It’s a powder that dissolves in water, creating a gloppy mix that coats the esophageal lining. At the Hoffman Center we generally dose it twice daily away from meals; a serving taken near bedtime seems to be particularly effective.